However, you are free to specify shorter intervals and to determine your own acceptable error limits depending on the application and accuracy requirements. You must check compliance with the error limits according to the ISO 8655 at least once a year as part of your test equipment monitoring or analytical quality assurance. You determine the pipette calibration intervals If a pipette fails a calibration "as found", the resulting effort can be huge – starting from checking all analysis results since the last calibration, up to repeating tests. Worn-out seals and O-rings (for multi-channel pipettes cones) are often not readily apparent. That’s why you are responsible for determining the calibration frequency, so that pipetting results continuously stay reliable. Users of instruments as a basis for routine verification of accuracy and consistencyīeing the manager of the lab, you know your rockstars best. Test laboratories for independent certification. 
Manufacturers as a basis for quality assurance. Who should do the pipette calibration according to ISO 8655? ISO 8655 criteria include the number of measurements and volumes, controls for room environment, and the permissible quality of the test chain. In most cases, users decide to use the error limits of the respective manufacturer, which usually are even tighter than the ISO 8655 limits. It defines the respective criteria and which maximum permissible error limits should be used at each volume tested. The ISO 8655 is an international standard for calibration and testing procedures of piston-operated volumetric apparatus (POVA) like pipettes, burettes, dilutors, and dispensers. Therefore, regular maintenance and calibration ensure the pipette is performing optimally in accordance with specifications and provide peace of mind to all involved. The calibration determines whether the pipette still delivers the accurate and precise volumes it is supposed to. 
The essential part of your lab rockstar’s preparation is the calibration.
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